NEPACOSS: Nepefenac 0.1% Eye Drops

💧 NEPACOSS Eye Drops

COMPOSITION:

Nepefenac 0.1% Eye Drops

PACKING:

5 ML

NEPACOSS is a next-generation non-steroidal anti-inflammatory eye drop (NSAID) that contains Nepafenac 0.1%, a prodrug specifically designed to target inflammation and pain in the anterior segment of the eye, particularly after cataract surgery and other ocular interventions.Nepafenac belongs to the aryl acetic acid class of NSAIDs and offers dual advantages — rapid corneal penetration and targeted intraocular anti-inflammatory action. Once inside the eye, it is enzymatically converted into its active metabolite Amfenac, which delivers potent and long-lasting cyclooxygenase (COX) enzyme inhibition, effectively suppressing the synthesis of prostaglandins — the key mediators of pain and inflammation.

💊  Indications:

• Post-operative inflammation after cataract surgery
• Prevention and treatment of cystoid macular edema (CME)
• Ocular pain and redness following surgery or laser procedures
• Inflammatory conditions of the anterior segment of the eye
• Post-laser photocoagulation inflammation
• Alternative to corticosteroids where steroid-sparing agents are preferred

⚙️ Mode of Action:

Nepafenac is a unique, next-generation non-steroidal anti-inflammatory drug (NSAID) formulated specifically for ophthalmic use. It is classified as a topical NSAID prodrug, designed to penetrate ocular tissues efficiently and provide powerful anti-inflammatory relief, particularly after ocular surgeries such as cataract extraction.What sets Nepafenac apart from traditional NSAIDs is its prodrug nature — meaning it remains pharmacologically inactive until it is converted to its active form inside the eye. This design enhances its ability to cross the corneal barrier, reduces surface irritation, and delivers site-specific action deep within intraocular structures.

🩺 Doctor’s Tip:

“Nepafenac 0.1% is my preferred choice for post-cataract inflammation, especially in diabetic patients at risk of cystoid macular edema. NEPACOSS delivers reliable anti-inflammatory action with minimal side effects.”
— Dr. Manav Joshi, Cataract & Anterior Segment Surgeon